Abstract: Objective To investigate the efficacy of percutaneous choledocholithotomy for the treatment of patients with intrahepatic bile duct stones. Methods The clinical data of 894 patients with intrahepatic bile duct stones were analyzed between January 2013 and January 2017 in our hospital by retrospective cross-sectional study,and the percutaneous cholangiography and lithotripsy was performed after T tube drainage. All patients were followed-up for postoperative recurrence of stones by ultrasonography,and the risk factors of postoperative recurrence were analyzed by Logistic regression analysis. Results Out of the 894 cases,87 patients （9.7%） had recurrence of stones,and univariate analysis showed that the percentages of patients older than 60 years,the maximum diameters of gallstones greater than 1 cm,the numbers of gallstones more than 10, the bile duct dilatation,physical jaundice,the positive bile bacteria cultures and cholelithiasis or mixed stones in patients with recurrent stone were found be much higher than in those without （all P<0.05）;further multivariate analysis demonstrated that the age ≥60 years,the maximum diameter of gallstones ≥1cm,and the number of gallstones≥10 cases were the independent risk factors for the recurrence of postoperative stones. Conclusion Percutaneous choledochotomy lithotripsy has a good efficacy in dealing with patients with intrahepatic bile duct stones,and the patients with high risk factors for postoperative bile duct stone recurrence should be followed-up regularly for early diagnosis and management in time.

Key words: Hepatolithiasis, Percutaneous choledocholithotomy lithotripsy, Recurrence, Risk factors