Abstract: Objectivee To analyze the severity of coronary artery lesions and risk factors in patients with nonalcoholic fatty liver disease （NAFLD） complicated by coronary heart disease （CHD）. Methods 154 patients with NAFLD were recruited in our hospital between January 2015 and January 2017,and 71 were found with CHD by coronary angiogram. The degree of fatty liver was determined by altrasonography and/or CT scan. Logistic analysis was applied to screen the risk factors for CHD occurrence. Results There were statistically significant differences between the two groups as respect to the percentages of diabetes and smoking,and serum levels of FPG,TC,TG,ALT,AST,GGT,hs-CRP and HOMA-IR （t/x²=7.62,5.38,3.82,5.80,3.72,8.79,3.10,5.75,5.25,5.93, P<0.05 or P<0.01）;multivariate Logistic regression analysis showed that diabetes,FPG,TC,ALT,hs-CRP and HOMA-IR were the independent risk factors of CHD in patients with NAFLD （P<0.05 or P<0.01）;among 71 patients with CHD,there were 37 cases with mild,23 with moderate and 11 with severe NAFLD,and there were statistically significant differences among the three groups as to the percentages of single,double and three branches coronary artery lesions （x²=14.8,P<0.01）. Conclusion The incidence of CHD in patients with NAFLD is relatively higher,and clinicians must take the risk factors into consideration in clinical practice in order to decrease the morbidity and mortality of heart diseases.

Key words: Nonalcoholic fatty liver disease, Coronary heart disease, Risk factors, Severity of coronary artery lesions