JOURNAL OF PRACTICAL HEPATOLOGY ›› 2019, Vol. 22 ›› Issue (2): 301-306.doi: 10.3969/j.issn.1672-5069.2019.02.038

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Noninvasive diagnosis and assessment of patients with nonalcoholic steatohepatitis

Xie Xiao, Lu Lungen   

  1. Department of Gastroenterology,Shanghai General Hospital,JiaoTong University School of Medicine,Shanghai 200080
  • Received:2018-01-18 Online:2019-03-10 Published:2019-03-19

Abstract: Nonalcoholic fatty liver disease (NAFLD) includes a spectrum of diseases ranging from nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH),cirrhosis and eventually to hepatocellular carcinoma (HCC). NASH has an increased risk for advanced cirrhosis and HCC,so there has been an urgent need to accurately distinguish between NAFL and NASH and intervene its further development in early time. In recent years,many noninvasive diagnostic methods including serological markers and imaging examination were applied in clinical practice trying to replace liver biopsy. This article reviews the noninvasive diagnosis and evaluation of NASH.

Key words: Nonalcoholic fatty liver disease, Nonalcoholic steatohepatitis, Noninvasive diagnosis, Assessment