放射性肝损伤患者肝脏磁共振扩散加权成像表现特征分析

doi:10.3969/j.issn.1672-5069.2019.03.016

Abstract

Abstract: Objectiv The aim of this study was to investigate the diagnostic value of diffusion-weighted magnetic resonance imaging in patients with radiation-induced liver injury （RILI） with underlying hepatocelullar carcinoma （HCC）. Methods 90 patients with histologically proven HCC were admitted to our hospital between January 2015 and June 2017,and RILI were confirmed by ultrasound-guided liver biopsies in 47 patients after radiotherapy. The pathological results showed the patients with acute RILI in 14,subacute in 17 and chronic in 16. All patients received MRI checked-up. Results The MRI manifestations in patients with RILI was a patchy abnormal signal area consistent with the radiation therapy,with low signal on T1WI,high signal on T2WI,slightly high signal on diffusion weighted imaging （DWI） sequence,and moderate enhancement on intensified scan;the apparent diffusion coefficient（ADC） value in patients with acute RILI was（85.32±8.41）×10^-6mm^-2/s,significantly lower than （88.44±9.32）×10^-6mm^-2/s in patients with subacute or （101.28±10.01）×10^-6mm^-2/s in patients with chronic RILI（P<0.05）. Conclusion The application of diffusion-weighted MR imaging might help diagnose patients with RILI,which will benefit the patients with HCC undergoing radiotherapy.

Key words: Hepatoma, Radiation induced liver injury, Magnetic resonance imaging, Diffusion-weighted imaging, Diagnosis

Peng Xinjian, Xiao Yuhui, Xu Siding. Diagnostic value of diffusion-weighted magnetic resonance imaging in patients with radiation-induced liver injury with underlying hepatocelullar carcinoma[J]. JOURNAL OF PRACTICAL HEPATOLOGY, 2019, 22(3): 373-376.

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Diagnostic value of diffusion-weighted magnetic resonance imaging in patients with radiation-induced liver injury with underlying hepatocelullar carcinoma

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