基于Exchange血流动力学模型的MRI扫描参数诊断肝硬化临床价值分析*

doi:10.3969/j.issn.1672-5069.2019.05.021

Abstract

Abstract: Objective To investigate the clinical value of MRI enhanced exchange hemodynamic model in evaluating liver cirrhosis. Methods

Results Out of 60 patients with chronic hepatitis B and chronic hepatitis C,the histopathological examination showed that fibrosis S1 in 3,S2 in 3,S3 in 1 and S4 in 53;the Ktrans and Ve in patients with advanced fibrosis decreased,while HPI,MTT and TTP increased significantly as compared to those without （P<0.05）;ROC analysis showed that Ktrans,HPI,MTT and TTP had a high efficacy in diagnosing liver cirrhosis（P<0.05）. Conclusion Several quantitative parameters can be obtained in DCE-MRI based on double-input and double chamber exchange hemodynamics model,which might be good parameters in guiding the diagnosis of patients with liver cirrhosis.

Key words: Liver cirrhosis, Magnetic resonance imaging, Exchange model, Diagnosis

Huang Hanjun, Lu Fengrong, Zhang Can. Clinical value of MRI scanning based on exchange hemodynamics model in evaluating liver cirrhosis[J]. Journal of Practical Hepatology, 2019, 22(5): 696-699.

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Clinical value of MRI scanning based on exchange hemodynamics model in evaluating liver cirrhosis

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