Abstract: Objective To observe the clinical efficacy of biliary stent placement under endosocopic retrograde cholangiopancreatography （ERCP） in the treatment of elderly patients with extrahepatic biliary malignant obstruction. Methods Sixty elderly patients with extrahepatic malignant biliary obstruction were admitted to our hospital between October 2014 and October 2017,30 in control received percutaneous transhepatic cholangiography （PTCD） treatment,while other 30 in observation group received ERCP biliary metal stent implantation. All patients were followed-up for 12 months. Results The stent patency period in the observation group was（225.4±52.6） days,significantly longer than[（156.7±44.2） days,P<0.05] in control group,and hospitalization stay was （12.3±2.4） days,significantly shorter than [（19.9±4.1） days,P<0.05] in control group;total serum bilirubin level 2 weeks after operation in the observation group was（110.2±60.1） μmol/L,significantly lower than[（149.8±64.5） μmol/L,P<0.05],serum alkaline phosphatase level was （216.8±127.6） IU/L,significantly lower than [（312.9±149.5） IU/L,P<0.05],and serum glutamyltransferase level was（196.5 ±100.5） IU/L,significantly lower than[（269.8 ±121.3） IU/L,P<0.05] in the control group;the incidence of post-operational complications was 10.0%,much lower than 33.3% （P<0.05） in the control,and 1-yr survival was 30.0%,much higher than 10.0% （x²=3.922,P=0.045） in the control. Conclusion The elderly patients with malignant extrahepatic biliary obstruction received ERCP biliary stent implantation might be efficacious in a short-term observation,which could shorten hospitalization stay,and prolong survival.

Key words: Malignant extrahepatic biliary obstruction, Endoscopic retrograde cholangiopancreatography, Percutaneous transhepatic biliary drainage, Elderly, Therapy