Abstract: Objective To investigate the clinical efficacy of hepatectomy and extravascular exfoliation in treatment of patients with giant hepatic hemangioma. Methods The clinical data of 82 patients with giant hepatic hemangioma admitted to our hospital between May 2014 and April 2016 were retrospectively analyzed，and 41 patients received hepatectomy and another 41 received extravascular exfoliation. All patients were followed-up for one year. Results The operative time，intraoperative blood loss，intraoperative blood transfusion，hepatic blood flow blocking time and hospital stay were （2.3±1.1） h，（885.2±387.5） ml，（928.7±412.4） ml，（21.4±9.6） min and （14.2±3.2） d in patients receiving exfoliation and（3.3±1.1） h，（1567.5±751.4） ml，（1896.4±852.4） ml，（27.5±8.2） min and（16.5±3.5） d in patients receiving hepatectomy（all P<0.05）；the incidence rate of postoperative complications was 14.6% in patients receiving exfoliation and 34.2% in patients receiving hepatectomy （P<0.05）；at the end of 1 year follow-up，one patient had recurrent hepatic hemagioma，11 lost and 29 had hepatic hemagioma disappeared in patients receiving hepatectomy，and one had recurrent hemagioma，8 lost and 32 had hemagioma disappeared in patients receiving tumor exfoliation. Conclusions Hepatectomy and extravascular exfoliation can be applied to the removal of giant hepatic hemangioma，while the latter has the advantages of relatively simple operation，small surgical trauma，little blood loss，short liver blood flow blocking time，rapid postoperative recovery and few postoperative complications.

Key words: Hepatic hemangioma, Hepatectomy, Extravascular exfoliation, Therapy