JOURNAL OF PRACTICAL HEPATOLOGY ›› 2016, Vol. 19 ›› Issue (1): 117-120.doi: 10.3969/j.issn.1672-5069.2016.01.034

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Research advances in severe alcoholic hepatitis

Zhu Bing, Liu Limin, Liu Honglin   

  1. Liver Failure Treatment and Research Center,302 Hospital of PLA,Beijing 100039, China
  • Received:2015-05-10 Online:2016-01-10 Published:2016-02-04

Abstract: The cornerstone of therapy for alcoholic hepatitis are abstinence and nutritional support. Many therapeutic interventions have been studied in alcoholic hepatitis but have been unable to show convincing benefit. These interventions included, Corticosteroids,Pentoxifylline,N-acetylcysteine,inhibitors of TNF-α,etc. High quality clinical trials research is essential in China. Liver transplantation(LT) confers a survival benefit in patients with ALD. However,alcohol relapse after transplantation remains a critical issue and drinking habits of transplanted patients need to be routinely screened.

Key words: Severe alcoholic hepatitis, therapy, review