Abstract: Objective To explore the research hotspots and subject structure of non-alcoholic fatty liver diseases （NAFLD） in China in the past decade. Methods The key words of articles in NAFLD field were retrieved in Chinese science citation database（CSCD） from January 2004 to December 2013. Word-frequency analysis, factor analysis and co-words clustered analysis were applied and statistic analysis was performed using excel 2010 and SPSS17.0. Results Eight hundred and fifty-two articles in presence of keywords about NAFLD were included and 40 high-frequency words were selected,which accounted for 70.2% of all relevant papers. The co-word clustered analysis showed that there were 9 hot subjects about NAFLD during last 10 years including insulin-sensitizing drugs,ultrasonography,epidemiology and risk factors,animal models,pathogenesis and traditional Chinese medicine,insulin resistance,Chinese medicine research,as well as gene and clinical treatment studies. Conclusions The co-word clustered analysis of research hotspots helps to understand the developmental of NAFLD in China.

Key words: Non-alcoholic fatty liver disease, Co-word clustered analysis, Factor analysis, Research hotspots