Abstract: Objective The aim of this study was to investigate the clinical value of three-dimensional magnetic resonance cholangiopancreatography (3D-MRCP) in the diagnosis of infantile biliary atresia (BA).Methods 24 children with suspected BA were admitted to our hospital between April 2016 and April 2020, and all underwent routine MRI and 3D-MRCP examination. The diagnostic efficacy of MRCP was evaluated by histopathological examination as a gold standard.Results 24 children with suspected BA were successfully completed surgery, andthe pathological examination showed BA in 22 (91.7%)children, including BA type Ⅰ in 2 (8.3%), BA type Ⅱ in2(8.3%) and type Ⅲ in 18(75.0%), choledochal cyst in 1 (4.2%) and normal biliary system in 1(4.2%); the 3D-MRCPdiagnosed BA in 21, choledochal cyst in 1, while misdiagnosed BA as choledochal cyst in 1, and misdiagnosed infantile hepatitis syndrome with normal biliary tract system as BA in 1; the sensitivity of 3D-MRCP in the diagnosis of BA was 95.5%, with the specificity of 50.0%, the accuracy of 95.8%,the positive predictive value of 95.5%, the negative predictive value of 50.0%, and the Kappa value of consistency with pathological diagnosis was 0.455 (P<0.05).Conclusion The application of 3D-MRCP has a high diagnostic efficiency for infants with BA, which could guide the clinicians dealing with this entity appropriately early.

Key words: Biliary atresia, Three-dimensional magnetic resonance cholangiopancreatography, Diagnosis