磁共振增强扫描弥散加权成像对肝脏良恶性肿瘤的鉴别诊断价值研究

doi:10.3969/j.issn.1672-5069.2021.02.030

Abstract

Abstract: Objective The aim of this study was to evaluate the clinical value of diffusion-weighted magnetic resonance imaging (DWI) in diagnosing patients with focal lesions of liver (FLL).Methods A total of 80 patients with FLL were collected and they received MRI and DWI, and all received hepatectomy. The MRI diagnosis was estimated by histopathological examination.Results Out of the 80 patients with FLL, the histopathological examination showed that hepatocellular carcinoma (HCC) in 28 patients, liver metastasis in 24, hepatic hemangioma in 19 and hepatic cyst in 9; When b=50 s/ mm³, the apparent diffusion coefficient (ADC) of region of interest (ROI) in HCC and in liver metastasis were(2.42±0.21) and (2.45±0.35), both significantly lower than 【(2.65±0.37) and (2.71±0.37), respectively, P<0.05】 in patients with hepatic hemangioma and hepatic cyst, when b=400 s/ mm³, the ADC in patients with HCC and liver metastasis were (2.03±0.22) and (2.17±0.23), both significantly lower than 【(2.48±0.34) and (2.49±0.24), respectively, P<0.05】 in patients with hepatic hemangioma and hepatic cyst, and when b=800 s/ mm³, the ADC in patients with HCC and liver metastasis were(1.75±0.26) and (1.82±0.18), also both significantly lower than 【(2.27±0.27) and (2.30±0.16), respectively, P<0.05】 in patients with hepatic hemangioma and hepatic cyst; the diagnostic accuracy of HCC, liver metastasis, hepatic hemangioma and hepatic cyst by MRI and DWI combination were 96.4%, 100.0%, 100.0% and 100.0%, significantly higher than [(71.4%, 75.0%, 68.4% and 66.7%), respectively P<0.05] by intensified MRI or [(53.6%, 45.8%, 57.9% and 55.6%), respectively, P<0.05] by DWI alone.Conclusion The diffusion-weighted magnetic resonance imaging in differentiating benign and malignant focal lesions of liver is promising and practical in clinical practice, which might help the clinicians dealing with the patients with FLL appropriately and improve the prognosis.

Key words: Focal lesion of liver, Magnetic resonance imaging, Diffusion weighted imaging, Diagnosis

Dai Xiaobing, Liu Qiyu, Wu Junhui. Diagnosis of focal lesions of liver by diffusion-weighted magnetic resonance imaging[J]. Journal of Practical Hepatology, 2021, 24(2): 268-271.

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Diagnosis of focal lesions of liver by diffusion-weighted magnetic resonance imaging

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