应用超声单模态融合成像技术指导微波消融治疗原发性肝癌即时疗效评价的价值研究*

doi:10.3969/j.issn.1672-5069.2020.04.030

Abstract

Abstract: Objective The aim of this study was to investigate the application of ultrasound single mode fusion imaging (USMFI) in the immediate evaluation of microwave ablation (MWA) in treatment of patients with primary liver cancer (PLC). Methods The clinical data of 88 patients with PLC were recruited in our hospital from March 2018 through December 2019, and all underwent MWA treatment. During MWA procedures, the USMFI guidance was performed in 44 patients, and CT/MRI multimodal fusion imaging was performed in other 44 patients.Results The registration time in US-guided group was (3.8±1.3) minutes, statistically significantly shorter than (5.2±1.7) minutes in CT/MIR-guided group (P<0.05), and the success rates of fusion imaging were 63.6% vs. 56.8%, not significantly different(P>0.05); 52 foci out of 44 patients in US-guided group were found and the successful fusion imaging was obtained in 36 foci(69.2%), and 54 out 44 patients in CT/MRI-guided group were found and the successful fusion was got in 32 foci (59.3%,P>0.05); the complete ablation rates were 97.7% and 93.2% in the two groups(P>0.05) and the incidences of compliattions such as fever, local pain, bile duct bleeding and bile leakage were 9.1%, 20.5%, 4.5% and 0.0% vs. 13.6%, 27.3%, 9.1% and 2.3%, respectively(P>0.05) in the two groups; at the end of 3 to 20 month followed-up, 32 (72.7%) patients in US-guided group survived with total survival (OS) of 15.1(5.0, 20.0) months and with progress free survival (PFS) of 12.8(4.9, 20.0)months, and 32 (72.7%) patients in CT/MRI-guided group survived with OS of 14.2(4.8, 20.0) months, and PFS of 13.3(4.7, 20.2) months (Log rank x²=0.592, P=0.442; x²=1.103, P=0.294). Conclusion Both the single-mode ultrasound fusion imaging and CT/MRI multi-mode fusion imaging could be applied to guide the MWA in the treatment of patients with PLC, but the former is relatively simple and cheap, and should be chosen first.

Key words: Hepatoma, Microwave ablation, Uultrasound single-mode fusion imaging, CT/MRI multi-mode fusion imaging, Efficacy evaluation

Meng Haisheng, Hu Dongmei, Wang Haitao, et al. Application of ultrasound single mode fusion imaging in the immediate evaluation of microwave ablation in treatment of patients with primary liver cancer[J]. Journal of Practical Hepatology, 2020, 23(4): 572-575.

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Application of ultrasound single mode fusion imaging in the immediate evaluation of microwave ablation in treatment of patients with primary liver cancer

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