Abstract: Objective To investigate the diagnostic efficacy of abdominal CT and endoscopic ultrasonography （EUS） examination in patients with chronic pancreatitis （CP）. Methods 78 patients with CP were recruited in this study between May 2012 and March 2017,and all of them were examined by EUS and abdominal CT. The diagnostic efficacy was analyzed by ROC curve. Results The histopathological examination showed that there were 28 patients with CP stage 1, 24 with CP stage 2,and 26 with CP stage 3; the AUC by EUS in diagnosing patients with CP stage 1 was 0.85（95%CI：0.75-0.92）,with the sensitivity （Se） of 85.7%,specificity （Sp） of 84.0%,and accuracy （Ac） of 84.6%,while the AUC by CT examination was 0.72（95%CI：0.61-0.82）,with the Se of 60.7%,Sp of 88.0%,and Ac of 78.2%; the AUC by EUS in diagnosing patients with CP stage 2 was 0.81（95%CI：0.70-0.89）,with Se of 79.2%,Sp of 81.5%,and Ac of 80.8%,while the AUC by CT was 0.73（95%CI：0.62~0.82）,with Se of 62.5%,Sp of 85.2%,and Ac of 78.2%; the AUC by EUS in diagnosing CP stage 3 was 0.75（95%CI：0.64-0.84）,with Se of 84.6%,Sp of 85.2%,and Ac of 85.0%,while the AUC by CT was 0.69（95%CI：0.57-0.79）,with Se of 69.2%,Sp of 88.9%,and Ac of 82.5%. ConclusionThe application of EUS and CT in the diagnosis of patients with CP is both highly efficient,and we recommend the EUS examination especially in patients with early CP in clinical practice.

Key words: Chronic pancreatitis, Clinical staging, Endoscopic ultrasonography, Computed tomography, Diagnosis