Abstract: Objective To investigate the effect of Xueshuantong,a herbal compound,on hepatic arterial blood flow and resistance index in patients after orthotopic liver transplantation （OLT）. Methods 40 patients with benign end-stage liver disease received OLT,and 20 was administered with Xueshuantong injection intravenously,and another 20 without after OLT. The hepatic artery blood flow and resistance index were measured by color Doppler sonography. Results The hepatic artery blood flow in patients receiving Xueshuantong at the end of 1 month,6 months and 18 months were 51.22±12.11 cm/s,61.32±11.87 cm/s and 65.38±12.76 cm/s,significantly higher than 47.181±4.25 cm/s,51.33±13.24 cm/s and 53.45±11.43 cm/s in the control（P<0.05）,and the hepatic artery resistance index were 0.66±0.13,0.62±0.12 and 0.68±0.11,significantly lower than 0.72±0.14,0.71±0.11 and 0.75±0.14 in the control（P<0.05）;serum bilirubin and ALT levels were significantly lower than those in the control group（P<0.05）. Conclusion Application of Xueshuantong injection can improve the hepatic artery blood flow,decrease resistance index and improve the liver function in patients after OLT.

Key words: Liver transplantation, Xueshuantong, Hepatic artery blood flow, Resistance index