JOURNAL OF PRACTICAL HEPATOLOGY ›› 2016, Vol. 19 ›› Issue (3): 373-376.doi: 10.3969/j.issn.1672-5069.2016.03.033

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Chronic kidney disease in patients with nonalcoholic fatty liver diseases

Lei Ting, Li Liangping   

  1. North Sichuan Medical College,Nanchong 637100,Sichuan Province,China
  • Received:2015-08-14 Online:2016-05-10 Published:2016-05-20

Abstract: Non-alcoholic fatty liver diseases (NAFLD) is an acquired metabolic stress-induced liver diseases associated with insulin resistance and genetic susceptibility,which has become one of the global public health problems. Accumulating evidence suggests that NAFLD may be associated with an increased prevalence and incidence of chronic kidney disease (CKD). In this review,the evidence of NAFLD related to CKD,and the putative mechanisms by which nonalcoholic fatty liver disease contributes to kidney damage will be reviewed,and we hope it will provide guidance and recommendations for more comprehensive management of patients with nonalcoholic fatty liver disease or chronic kidney disease.

Key words: Nonalcoholic fatty liver disease, Chronic kidney disease, Metabolic syndrome, Insulin resistance