JOURNAL OF PRACTICAL HEPATOLOGY ›› 2018, Vol. 21 ›› Issue (2): 313-316.doi: 10.3969/j.issn.1672-5069.2018.02.047

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Glucagon-like peptide-1 in melioration of non-alcoholic fatty liver disease

Xin Fengzhi, Cao Haixia, Fan Jiangao   

  1. Department of Gastroenterology,Xinhua Hospital,JiaoTong University School of Medicine,Shanghai 200092,China
  • Received:2017-01-10 Online:2018-03-10 Published:2018-03-19

Abstract: Glucagon-like peptide-1 receptor agonists could meliorate hepatic lipid deposition and histological damage by regulating lipid metabolism,inflammation and autophagy in pathogenesis of non-alcoholic fatty liver disease (NAFLD),which may serve as a new option for treatment of patients with NAFLD.

Key words: Non-alcoholic fatty liver disease, Glucagon-like peptide 1, Pathogenesis