Abstract: Objective To investigate the diagnostic value of color Doppler ultrasound semi-quantitative score in the diagnosis of patients with viral hepatitis B liver cirrhosis. Methods 136 patients with hepatitis B liver cirrhosis and 364 with hepatitis B were recruited between August 2014 and December 2015 in this study. The portal vein flows,flow rates and internal diameters and semi-quantitative scores were conducted for the diagnostic validity of color Doppler ultrasound. Results The portal venous flow,velocity and diameter in cirrhotic group were （86.3±7.5） ml/min,（3.8±0.1） cm/s,（11.5±1.4） mm,significantly higher than those in patients with hepatitis B [（62.3±6.4） ml/min,（3.1±0.1） cm/s,（8.7±1.6） mm,P<0.05];the distinct of hepatic vein,hepatic surface,gallbladder,liver morphological edge,liver parenchyma,intrahepatic ligament,and the size of spleen and the total scores in patients with hepatitis B were （1.1±0.3）,（1.2±0.3）,（1.1±0.2）,（1.0±0.4）,（1.1±0.5）,（1.0±0.2）,（1.4±0.4）,（8.1±0.3）,significantly lower than in cirrhotic group [（2.6±0.3）,（4.1±1.2）,（1.9±0.3）,（1.9±1.0）,（2.7±0.4）,（1.4±0.5）,（4.1±1.6）,（15.1±1.1）,P<0.05];the sensitivity by color Doppler ultrasonic semi quantitative score in diagnosis of early hepatitis B liver cirrhosis was 96.3%,the specificity was 92.3%,the positive predictive value was 82.4%,and the negative predictive value was 98.5%. Conclusion Color Doppler ultrasound semi-quantitative score has high specificity and sensitivity in the diagnosis of early hepatitis B liver cirrhosis, which might be used as an effective method for clinical screening in patients with chronic hepatitis B.

Key words: Liver cirrhosis, Hepatitis B, Color Doppler ultrasound, Semi-quantitative score