术前血清miR-221水平对肝细胞肝癌R0切除术后早期复发的预测价值*

doi:10.3969/j.issn.1672-5069.2014.05.028

Abstract

Guo Xiaodong, Yu Lingxiang, Li Ruisheng. Serum miR-221 levels predicts short-term survival after R0 resection in patients with hepatocellular carcinoma[J]. JOURNAL OF PRACTICAL HEPATOLOGY, 2014, 17(5): 543-545.

References

[1] Block T,Mehta A S,London W T. Hepatocellular carcinoma of the liver. Cancer Biomark,2010,9（1-6）:375-383.
[2] 吴力群,王祖森,胡维昱,等. 528例原发性肝细胞癌患者肝切除术后1年生存分析. 中华普通外科杂志,2012,27（2）:92-95.
[3] 王红阳. 肝癌诊断与预后判断的分子标志物. 中华肝脏病杂志,2011,19（4）:241-243.
[4] Ju J,Jiang J,Fesler A. miRNA:the new frontier in cancer medicine. Future Med Chem,2013,5（9）:983-985.
[5] Li J,Wang Y,Yu W,et al. Expression of serum miR-221 in human hepatocellular carcinoma and its prognostic significance. Biochem Biophys Res Commun,2011,406（1）:70-73.
[6] 吴育连,苏昆仑,董鑫,等. 肝癌切除术后早/晚期复发的危险因素与治疗. 中华肝胆外科杂志,2006,12（6）:370-373.
[7] Moriguchi M,Takayama T,Higaki T,et al. Early cancer-related death after resection of hepatocellular carcinoma. Surgery,2012,151（2）:232-237.
[8] 王洁,孟运运,汪茂荣. 血清AFP,GGT-Ⅱ和GGT联合检测诊断原发性肝癌的价值探讨. 实用肝脏病杂志,2012,15（6）:545-547.
[9] 王寿明,高蕾,于乐成,等. 甲胎蛋白异质体对肝癌诊断及疗效评估价值研究进展. 实用肝脏病杂志,2011,14（6）:479-481.
[10] Mitchell PS,Parkin RK,Kroh EM,et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A,2008,105（30）:10513-10518.
[11] Pineau P,Volinia S,Mcjunkin K,et al. miR-221 overexpression contributes to liver tumorigenesis. Proc Natl Acad Sci U S A,2010,107（1）:264-269.
[12] Di Leva G,Gasparini P,Piovan C,et al. MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer. J Natl Cancer Inst,2010,102（10）:706-721.
[13] Kawaguchi T,Komatsu S,Ichikawa D,et al. Clinical impact of circulating miR-221 in plasma of patients with pancreatic cancer. Br J Cancer,2013,108（2）:361-369.
[14] le Sage C,Nagel R,Egan D A,et al. Regulation of the p27（Kip1）tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation. EMBO J,2007,26（15）:3699-3708.
[15] 雷永红,吕文平,王海,等.肝细胞癌患者血清miR-221和miR-122的检测及其临床意义.河北医科大学学报,2013,34（5）:522-525.

Serum miR-221 levels predicts short-term survival after R0 resection in patients with hepatocellular carcinoma

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