JOURNAL OF PRACTICAL HEPATOLOGY ›› 2010, Vol. 13 ›› Issue (6): 433-435.doi: 10.3969/j.issn.1672-5069.2010.06.012

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Relationship between cardiac diastolic function and live function in patients with nonalcoholic steatosis hepatitis

HUANG Jian,HUANG Qun,CHEN Xiaozhu,et al.   

  1. Department of Gastroenterology,Futian People’s Hospital,Affilicated to Guangdong Medical College,Shenzhen 518033,China
  • Received:2010-09-09 Online:2010-12-10 Published:2016-04-18

Abstract: Objective To explore the relationship between cardiac diastolic function and liver function in patients with nonalcoholic steatosis hepatitis(NASH). Methods 64 patients with simple fatty liver(SFL),56 patients with NASH and 120 matched healthy controls were examined by color Doppler echocardiography in this study. Diastolic cardiac dysfunction(DCD)was defined when the patient had an E/A ratio less than 1. Results The incidence of diastolic cardiac dysfunction in patients with NASH was significantly higher than that in patients with SFL and normal controls(44.6% vs. 10.9% and 5.0%,P<0.01);NASH patients had an lower E/A ratio than normal controls and SFL patients(1.0±0.3 vs. 1.3±0.20 and 1.3±0.20,P<0.01);and the patients with NASH had a significantly higher level of serum ALT,AST and GGT than in patients with SFL.Conclusion DCD is commonly seen in patients with NASH.

Key words: Nonalcoholic fatty liver disease, Nonalcoholic steatosis hepatitis, Cardiac diastolic dysfunction, Color doppler echocardiography, Live function