血清MicroRNA作为生物学标记物对肝硬化诊断及预后判断研究进展

doi:10.3969/j.issn.1672-5069.2016.05.033

摘要/Abstract

摘要： MicroRNA（miRNA）在生物体生长、发育及疾病发生发展等过程中都起着十分重要的作用。近期的实验表明,部分血清miRNAs在肝硬化患者水平差异较大,对肝硬化的诊断具有高度敏感性和特异性,提示血清miRNAs可作为潜在的生物学标记物用于肝硬化的临床诊断及预后判断。

关键词: 肝硬化, miRNA, 诊断, 预后判断

Abstract: MicroRNAs（miRNAs）have emerged as master regulators in several biological processes. More and more studies have shown that serum miRNAs levels differ in liver cirrhosis. Serum miRNAs may serve as a potential biomarker for dignosis and prognosis of patients with liver cirrhosis

Key words: Liver cirrhosis, miRNA, Diagnosis, Prognosis

麻树霖陈征综述, 刘晓峰审校. 血清MicroRNA作为生物学标记物对肝硬化诊断及预后判断研究进展[J]. 实用肝脏病杂志, 2016, 19(5): 629-632.

Ma Shulin, Liu Xiaofeng.. Serum MicroRNA in diagonsis of patients with liver cirrhosis[J]. JOURNAL OF PRACTICAL HEPATOLOGY, 2016, 19(5): 629-632.

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