抗线粒体抗体对原发性胆汁性肝硬化诊断价值研究进展

doi:10.3969/j.issn.1672-5069.2014.02.030

摘要/Abstract

摘要： 原发性胆汁性肝硬化是一种原因不明的慢性胆汁淤积性肝病，抗线粒体抗体检测对其诊断有较高的特异度和灵敏度。近年来，随着临床医师认识的提高以及自身抗体检测的普及，原发性胆汁性肝硬化的发病率及患病率有逐年增加的趋势，早期诊断及治疗干预对该病的预后有重要意义。本文重点讨论抗线粒体抗体及其分型在原发性胆汁性肝硬化诊断中的意义。

关键词: 原发性胆汁性肝硬化, 抗线粒体抗体, 诊断

Abstract: Primary biliary cirrhosis is a chronic, slowly progressive cholestatic liver disease of unknown etiology. The antimitochondrial antibody detected in the blood is specific and wih high sensitivity for the diagnosis of PBC. Recent years,with the increased acknowledge of clinic phsicians and the popular of the detection of autoantibodies, the incidence and prevalence has increasing trend year by year,early diagnosis and treatment have great significance on the prognosis of the disease. This researth is focused on the significance of the antimitochondrial antibody and its subtypes in diagnosing of primary biliary cirrhosis.

Key words: Primary biliary cirrhosis, antimitochondrial antibody, Diagnosis

刘然综述，陆伦根审校. 抗线粒体抗体对原发性胆汁性肝硬化诊断价值研究进展[J]. 实用肝脏病杂志, 2014, 17(2): 218-220.

Liu ran review， Lu Lun-gen reviser. Advances of the researth of the value of antimitochondrial antibody in the diagnosis of primary biliary cirrhosis[J]. JOURNAL OF PRACTICAL HEPATOLOGY, 2014, 17(2): 218-220.

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