实用肝脏病杂志 ›› 2011, Vol. 14 ›› Issue (2): 127-128.doi: 10.3969/j.issn.1672-5069.2011.02.016

• 论著 • 上一篇    下一篇

肝硬化患者血钠水平与肝脏储备功能的关系探讨

孙玉珍,任敏,党新云,舒菊娟,董薇,占国清   

  1. 442100 湖北省房县人民医院感染病科(孙玉珍,任敏,党新云,舒菊娟,董薇);湖北医药学院附属人民医院肝病研究所(占国清)
  • 收稿日期:2010-12-13 出版日期:2011-04-10 发布日期:2016-04-15
  • 通讯作者: 占国清,E-mail: syrmhospital@yahoo.com.cn
  • 作者简介:孙玉珍 女,37岁,医学学士,主治医师。E-mail:243132695@qq.com

The relationship of serum sodium levels to liver functional reserve in patients with liver cirrhosis

SUN Yuzhen,REN Min,DANG Xinyun,et al.   

  1. Department of Infectious Diseases,People’Hospitol,Fang Country 442100,Hubei Province,China
  • Received:2010-12-13 Online:2011-04-10 Published:2016-04-15

摘要: 目的 探讨血钠水平与失代偿期肝硬化患者肝脏储备功能的关系。方法 回顾性分析150例失代偿期肝硬化并发低钠血症患者的临床资料,根据其入院时血钠水平分为轻、中、重度低钠血症,比较3组患者肝肾和凝血功能、Child-Pugh分级、主要并发症和预后。结果 血钠水平越低,患者血清总胆红素、尿素氮、肌酐、凝血酶原时间、Child-Pugh评分及主要并发症发生率越高,白蛋白越低(P<0.05或P<0.01),其病死率也越高。结论 失代偿期肝硬化患者血钠水平与肝脏储备功能相关。

关键词: 肝硬化, 低钠血症, 肝储备功能

Abstract: Objective To explore the relationship of serum sodium levels to liver functional reserve in patients with decompensated liver cirrhosis. Methods 150 decompensated liver cirrhosis patients with hyponatremia were analyzed retrospectively. The patients were divided into mild,moderate and severe hyponatremia groups according to their serum sodium levels. Results The more severe patients’serum hyponatremia,the higher their serum total bilirubin,urea nitrogen,creatinine,prothrombin time and Child-Pugh scores and the patients with severe hyponatremia had more major complications,and higher mortality. Conclusions The serum sodium levels in patients with decompensated liver cirrhosis reflect liver functional reserve.

Key words: Liver cirrhosis, Hyponatremia, Liver functional reserve