Betatrophin与非酒精性脂肪性肝病

doi:10.3969/j.issn.1672-5069.2023.06.041

摘要/Abstract

摘要： 目的非酒精性脂肪性肝病(NAFLD)是一种代谢应激性肝损伤。随着肥胖和代谢综合征(MetS)的流行,NAFLD已成为我国第一大慢性肝病。Betatrophin是一种新发现的与糖脂代谢和胰岛素抵抗(IR)等密切相关的分泌性糖蛋白,可能与NAFLD患者发病和病情进展密切相关。本文就Betatrophin在NAFLD发生发展过程中的作用和潜在的临床应用价值做一综述。

关键词: 非酒精性脂肪性肝病, Betatrophin, 糖脂代谢, 胰岛素抵抗

Abstract: Objective Nonalcoholic fatty liver diseases (NAFLD) is a kind of liver injury caused by metabolic stress. With the prevalence of obesity and metabolic syndrome (MetS), the NAFLD has become the most popular chronic liver disease in China. Betatrophin is a newly discovered glycoprotein closely related to glucose and lipid metabolism and insulin resistance (IR), which may be closely related to the onset and progression of NAFLD. This article reviewed the role of betatrophin in the process and development of NAFLD.

Key words: Nonalcoholic fatty liver diseases, Betatrophin, Glucose and Lipid metabolism, Insulin resistance

韩仕杉, 赵彩彦. Betatrophin与非酒精性脂肪性肝病[J]. 实用肝脏病杂志, 2023, 26(6): 930-933.

Han Shishan, Zhao Caiyan. Perspective of betatrophin in the development of nonalcoholic fatty liver diseases[J]. Journal of Practical Hepatology, 2023, 26(6): 930-933.

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