实用肝脏病杂志 ›› 2023, Vol. 26 ›› Issue (3): 445-448.doi: 10.3969/j.issn.1672-5069.2023.03.037

• 综述 • 上一篇    下一篇

慢性乙型肝炎合并非酒精性脂肪性肝病与肝细胞癌

苏佩华 综述, 宋枚芳, 赵彩彦 审校   

  1. 050051 石家庄市 河北医科大学第三医院感染科
  • 收稿日期:2022-03-07 出版日期:2023-05-10 发布日期:2023-05-08
  • 通讯作者: 赵彩彦,E-mail:zhaocy2005@163.com
  • 作者简介:苏佩华,女,27岁,硕士研究生。主要从事慢性肝病与肝癌的防治研究。E-mail:peihuasu2022@163.com

Is the incidence of hepatocellular carcinoma increased in patients with chronic hepatitis B and nonalcoholic fatty liver diseases?

Su Peihua, Song Meifang, Zhao Caiyan   

  1. Department of Infectious Diseases,Third Hospital,Hebei Medical University,Shijiazhuang 050051,Hebei Province, China
  • Received:2022-03-07 Online:2023-05-10 Published:2023-05-08

摘要: 随着肥胖、糖尿病患病率的升高,非酒精性脂肪性肝病(NAFLD)发病率逐渐升高。在慢性乙型肝炎(CHB)患者中,合并NAFLD的患者亦越来越多。慢性HBV感染和NAFLD均是导致肝细胞癌(HCC)的病因。CHB合并NAFLD可能增加HCC的发生风险。本文主要从CHB合并NAFLD与HCC的发生机制及其防控管理相关内容做一综述。

关键词: 肝细胞癌, 慢性乙型肝炎, 非酒精性脂肪性肝病, 发病机制, 管理

Abstract: With the increasing prevalence of obesity and diabetes, the incidence of nonalcoholic fatty liver diseases(NAFLD)has gradually increased. More and more patients with chronic hepatitis B (CHB) are complicated with NAFLD. The chronic HBV infection and NAFLD are both causes of hepatocellular carcinoma(HCC), and the patients with CHB and NAFLD might have the increased risk of HCC. In this article, we review the hepatocarcinogenesis, prevention and control management of patients with CHB and NAFLD, and patients with HCC.

Key words: Hepatocellular carcinoma, Hepatitis B, Nonalcoholic fatty liver diseases, Pathogenesis, Management