关键词: 肝硬化, 慢性乙型肝炎, 彩色多普勒超声, 诊断

Abstract: Objectiv The aim of this stud was to investigate the diagnostic value of color Doppler ultrasonography in diagnosis of patients with hepatitis B cirrhosis. Methods 80 patients with hepatitis B-induced liver cirrhosis（LC） and 50 patients with chronic hepatitis B（CHB） were recruited in our hospital between July 2017 and July 2018,and all of them underwent color Doppler ultrasonography. The sonographic features,semi-quantitative ultrasound scores and portal hemodynamics were compared between the two groups. Results The scores of liver capsule,hepatic parenchymal echo,intrahepatic ligament,gallbladder wall,spleen area,hepatic vein resolution and hepatic edge morphology in patients with LC were（4.1±1.1）,（2.5±0.5）,（1.5±0.2）,（2.7±0.3）,（2.6±0.6）,（2.7±0.4） and （2.3±0.3）,significantly higher than [（1.4±0.3）,（1.4±0.3）,（1.0±0.1）,（1.2±0.2）,（1.3±0.3）,（1.2±0.1） and （1.0±0.3）,respectively,P<0.05] in patients with CHB;the diameter of the portal vein was （1.5±0.1） cm,significantly wider than [（1.1±0.1）cm,P<0.05],the blood flow velocity was（12.6±1.3） cm/s,significantly slower than [（22.3±3.6）cm/s,P<0.05] and the blood flow was （1114.4±117.4） ml/min,significantly less than [（1278.3±121.4） ml/min,P<0.05] in patients with CHB; we set the semi-quantitative score of ultrasonography being greater than 15 as the cut-off-value of liver cirrhosis and the liver histological examination as the gold standard,the diagnostic sensitivity was 93.8%,the specificity was 88.0%,the positive predictive value was 92.6%,and the negative prediction was 89.8%. Conclusion The semi-quantitative scoring system by color Doppler ultrasonography can be effectively applied to the diagnosis of patients with hepatitis B-induced early liver cirrhosis.

Key words: Liver cirrhosis, Hepatitis B, Color Doppler ultrasonography, Diagnosis