关键词: 肝硬化, 胆囊结石, 腹腔镜胆囊切除术, 并发症, 危险因素

Abstract: Objective To analyze the clinical efficacy and related risk factors of complications in alcoholic liver cirrhosis patients with gallstone after laparoscopic cholecystectomy（LC）. Methods 120 alcoholic liver cirrhosis patients with gallstones were recruited and treated in our hospital between December 2013 and December 2016. The patients were divided into two groups,60 of them received cholecystectomyby conventional right upper abdominal incision,and another 60 underwent LC. The surgery parameters and postoperative complications in the two groups were compared,and univariate and multivariate Logistic regression analysis were used to analyze the related factors of postoperative complications in the LC group. Results The bleeding in LC group was（100.6±24.9） ml,lesser than （139.6±38.6） ml in conventional group （the difference was statistical significant,P<0.05）;the operative time was（53.9±18.6） min,much shorter than （76.2±23.1） min in the conventional group （the difference was statistical significant,P<0.05）;the postoperative exhaust time was（28.4±8.6） h,apparently shorter than（50.6±13.6） h in the conventional group（the difference was statistical significant,P<0.05）;the hospitalization time was （5.8±2.9） d,obviously shorter than （10.0±4.6） d in the conventional group （the difference was statistical significant,P<0.05）;the incidence of postoperative complications was 8.3%,significantly lower than 21.7% in the conventional group（the difference was statistical significant,P<0.05）;the gallbladder wall thickness,Calot triangle adhesion,surrounding organ adhesion and gallbladder neck stone were found to be the related risk factors for complications after LC,and the finding was confirmed by multivariate Logistic regression analysis.Conclusion LC has significant efficacy in treatment of alcoholic liver cirrhotic patients with gallbladder stones,and the main risk factors for postoperative complications occurrence are calot triangle adhesion,adhesion of peripheral organs,gallbladder neck stone and the increased thickness of gallbladder wall. Surgeon might pay attention to prevent the postoperative complications after LC by strict control of surgical process.

Key words: Alcoholic liver cirrhosis, Gallbladder stones, Laparoscopic cholecystectomy, Complications, Risk factors