实用肝脏病杂志 ›› 2014, Vol. 17 ›› Issue (1): 106-109.doi: 10.3969/j.issn.1672-5069.2014.01.034

• 综述 • 上一篇    下一篇

肠道菌群失调在慢性肝病发病中的作用研究进展

赵欣综述, 赵彩彦审校   

  1. 050051 石家庄市 河北医科大学第三医院感染病科
  • 收稿日期:2013-03-14 出版日期:2014-02-28 发布日期:2016-04-11
  • 通讯作者: 赵彩彦,E-mail:zhaocy2005@163.com
  • 作者简介:赵欣,女,26岁,硕士研究生。主要从事慢性肝病发病机制的研究。E-mail:superzhaoxin3693@126.com

Progress in dysbacteriosis in chronic liver diseases

Zhao Xin, Zhao Caiyan   

  1. Department of Infectious Diseases,3rd Hospital Afflilated to Hebei Medical Unviersity,Shijiazhuang 050051,China
  • Received:2013-03-14 Online:2014-02-28 Published:2016-04-11

摘要: 肠道菌群是肠道屏障的重要组成部分,在健康状态下肠道菌群与机体之间处于平衡状态。当某种原因引起机体内外环境发生变化破坏了该平衡状态时,即出现肠道菌群失调。肠道菌群失调可以促进各种慢性肝脏疾病的发生与发展。应用益生菌治疗能够改善肠道菌群失调,从而为治疗慢性肝脏疾病带来更好的疗效。

关键词: 肝硬化, 非酒精性脂肪性肝病, 酒精性肝病, 肠道菌群失调

Abstract: Intestinal flora is an important part of the intestinal barrier. Under healthy condition,a normal balance of intestinal flora is maintained, however, under pathological circumstances a number of factors can change the balance and result in dysbacteriosis. In turn dysbacteriosis promotes the progress and exacerbation of chronic liver diseases. Administration of probiotics can improve the balance of intestinal flora and help the recovery of chronic liver disease.

Key words: Cirrhosis, Non-alcoholic fatty liver disease, Alcoholic liver disease, Dysbacteriosis