实用肝脏病杂志 ›› 2012, Vol. 15 ›› Issue (1): 32-36.doi: 10.3969/j.issn.1672-5069.2012.01.011

• 肝硬化 • 上一篇    下一篇

门脉高压性胃病患者幽门螺杆菌感染率调查

杜建新, 蒋锦华, 芦 红   

  1. 467000 河南省平顶山市第二人民医院肝病科(杜建新); 胃镜室(芦红); 平顶山市疾病预防控制中心 (蒋锦华)
  • 收稿日期:2011-08-02 出版日期:2012-02-10 发布日期:2016-05-11
  • 作者简介:杜建新 男,43岁,医学学士,副主任医师。主要从事肝病的诊断和治疗学研究。E-mail:dujx618@163.com

The prevalence of Helicobacter pylori in patients with portal hypertensive gastropathy

Du Jianxin, Jiang Jinhua, Lu Hong   

  1. .Second People's Hospital,Pingdingshan 467000,Henan Province,China
  • Received:2011-08-02 Online:2012-02-10 Published:2016-05-11

摘要: 目的探讨幽门螺杆菌(Hp)与肝硬化并发胃和十二指肠病变的关系。方法采用快速尿素酶试验和改良的Giemsa染色法检测Hp感染。结果在264例肝硬化患者,Hp阳性183例(69.4%),在262例慢性胃炎(CG)患者,Hp阳性172例(66.4%,P>0.05);在79例肝硬化伴有PHG患者,Hp阳性60例(75.9%),在114例肝硬化不伴PHG患者,Hp阳性75例(65.8%),在37例肝硬化伴轻型PHG患者,Hp阳性26例(70.2%),在42例肝硬化伴重型PHG患者,Hp阳性34例(80.9%,P>0.05);在56例肝硬化伴十二指肠溃疡(DU)患者,Hp阳性48例(85.7%),在109例肝硬化不伴消化性溃疡(PU)患者,Hp阳性67例(61.4%,P<0.05);在125例DU患者,Hp阳性112例(89.6%);在28例肝硬化伴胃溃疡(GU)患者,Hp阳性20例(71.4%),在47例GU患者,Hp阳性43例(91.5%)。结论肝硬化伴DU患者Hp感染率较高。

关键词: 肝硬化, 幽门螺杆菌, 门脉高压性胃病, 十二指肠溃疡, 胃溃疡

Abstract: Objective To explore the prevalence of Helicobacter pylori in patients with portal hypertensive gastropathy. Methods Helicobacter pylori was detected by RUT. Results In 264 patients with liver cirrhosis,69.4% was Hp positive,and in 262 with chronic gastritis (CG),66.4% was positive(P>0.05);In 79 liver cirrhosis with PHG,75.9% was Hp positive;In 56 liver cirrhosis with duodenal ulcer(DU),85.7% was Hp positive,and in 109 with peptic ulcer(PU),61.4% was Hp positive;In 28 liver cirrhosis with gastric ulcer(GU),71.4% was Hp positive,and in 47 patient with GU,91.5% was Hp positive.Conclusion The prevalence of Hp infection is high in liver cirrohsis patients with DU.

Key words: Liver cirrhosis, Portal hypertensive gastropathy, Peptic ulcer, Helicobacter pylori