JOURNAL OF PRACTICAL HEPATOLOGY ›› 2015, Vol. 18 ›› Issue (2): 209-212.doi: 10.3969/j.issn.1672-5069.2015.02.030

• Orignal Article • Previous Articles     Next Articles

Spleen stiffness measurement in non-invasive diagnosis of patients with chronic liver diseases

Zeng Jing, Fan Jiangao   

  1. Department of Gastroenterology,Key Laboratory of Children’s Digestion and Nutrition,Xinhua Hospital, Affiliated to Shanghai JiaoTong University School of Medicine,Shanghai 200092,China
  • Received:2014-06-26 Online:2015-03-10 Published:2016-02-19

Abstract: Chronic liver diseases,having high morbidity and mortality,are important public-health problems worldwide. Chronic hepatitis may progress into advanced liver fibrosis,cirrhosis or even liver cancer. The correct evaluation of the severity of liver diseases is therefore necessary. However,the liver biopsy is invasive, and the measurement of hepatic venous pressure gradient is complicated. Recently,many studies suggest that non-invasive diagnostic techniques to measure the changes of liver and spleen stiffness are correlated with the severity and progression of liver diseases. This review mainly discuss the application of spleen stiffness measurement in non-invasive diagnosis of patients with chronic liver diseases.

Key words: Chronic liver diseases, Spleen, Stiffness, Portal hypertension