JOURNAL OF PRACTICAL HEPATOLOGY ›› 2015, Vol. 18 ›› Issue (3): 317-320.doi: 10.3969/j.issn.1672-5069.2015.02.030

• Orignal Article • Previous Articles     Next Articles

Immunopathogenesis of acute-on-chronic hepatitis B liver failure

Li Xiaodong, Xu Dongping   

  1. Medical school of Chinese PLA,Beijing 100853
  • Received:2014-11-11 Online:2015-05-10 Published:2016-02-19

Abstract: Acute-on-chronic liver failure (ACLF) refers to an acute decompensated liver function in patients with chronic liver diseases and the most common cause of ACLF in China is HBV infection. Activation of cytotoxic T lymphocytes and increased cytokines can cause immunopathogenetic injuries in liver tissues. This article mainly reviewed the immunopathogenesis progress of HBV related ACLF.

Key words: Acute-on-chronic liver failure, Hepatitis B, Immunopathogenesis