非编码RNA甲基化与肝癌发生发展关系研究进展*

doi:10.3969/j.issn.1672-5069.2018.06.042

Abstract

Abstract: Non-coding RNAs （ncRNAs） refer to the RNAs that don't encode proteins,while play an important role in the life activities of organisms. Methylation is the significant part of RNA transcription based on genome. The abnormal methylation of microRNA and lncRNA may be the key signals to influence the occurrence and development of hepatocellular carcinoma （HCC）. In this paper,the implication of non-coding RNA（microRNA and lncRNA） methylation in the development of HCC in recent years is reviewed.

Key words: Hepatocellular carcinoma, Non-coding RNA, Methylation, miRNA, lncRNA

Liu Xiaoni, Liu Xiuhong, Chen Dexi.. Non-coding RNA methylation in the carcinogenesis of hepatocellular carcinoma[J]. JOURNAL OF PRACTICAL HEPATOLOGY, 2018, 21(6): 991-994.

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Non-coding RNA methylation in the carcinogenesis of hepatocellular carcinoma

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