Abstract: Objective To investigate the efficacy of small incision of endoscopic sphincterotomy （SEST） and endoscopic papillary balloon dilatatio （EPBD） in treatment of patients with juxtapapillary duodenal diverticulum（JPDD） and common bile duct stones. Methods 82 patients with choledocholithiasis of JPDD were divided into study group and control group， with 41 cases in each group. The patients in the control group were treated with EST and in the study group were treated with SEST and EPBD. Results The one time success rate （90.24%） and the total success rate（95.12%） in the study group were higher than those in the control group （73.17% and 78.05%，respectively），and the mechanical lithotripsy rate was 12.20%，much lower than 31.71% in the control group （P<0.05）；the hospitalization stay in the study group was （7.98±1.14） days，much shorter than （11.03±1.39） days in the control group（P<0.05）；serum bilirubin levels in the two groups before and after operation had no significant difference （P>0.05）；The incidence rates of complications（9.76%） in the study group was lower than （36.59%） in the control group（P<0.05）. Conclusion Small endoscopic sphincterotomy and balloon dilation in the treatment of patients with juxtapapillary duodenal diverticulum accompanied by common bile duct stones has a good efficacy，with higher success rate of stone removal， shorter hospitalization stay，and lower incidence rate of complications.

Key words: Choledocholithiasis, Juxtapapillary duodenal diverticulum, Small endoscopic sphincterotomy, Balloon dilatation, Efficacy