Abstract: Objective To explore the application of indocyanine green （ICG） clearance test,single photon emission computed tomography （SPECT ） and three-dimensional resconstruction in patients with primary liver cancer before hemihepatectomy. Methods Clinical data of 50 patients with PLC who had underwent hemihepatectomy were collected and analyzed. Among them,twenty-six patients underwent preoperative evaluation of ICG clearance test,SPECT and three-dimensional reconstruction technique before operation as observation group,and twenty-four didn't get the evaluation as the control. The operative and postoperative indicators in the two groups were compared,and the differences of postoperative liver dysfunction and other complications were analyzed. Results The operative times in the observation and control were （134.2±40.7）min and（157.0±33.2）min,hospitalization days after operation were（12.2±4.7） d and（14.8±3.4） d,respectively,with the differences significantly different（P<0.05）,while the blood loss and tube drawing in the two groups were not significantly different（P>0.05）;the incidence of postoperative complications,such as bile leakage,ascites,pulmonary infection,infection of incisional wound and liver deficiency in the observation group was 19.2%,significantly lower than that in the control group（45.8%,P<0.05）. Conclusion The preoperative evaluation by ICG clearance test,SPECT and three-dimensional reconstruction is helpful in guiding hemihepatectomy in patients with PLC before operation.

Key words: Hepatoma, Hemihepatectomy, Preoperative evaluation, Liver dysfunction