Abstract: Objective The aim of this study was to investigate prevalence of nutrition and sarcopenia in patients with hepatitis B-induced liver cirrhosis (LC). Methods 156 patients with hepatitis B-induced LC were encountered in our hospital between January 2019 and December 2023, subjective global assessment (SGA) was applied to screen nutritional risk, and sarcopenia was diagnosed based on criteria proposed out by Asian Working Group for Sarcopenia 2019 (AWGS2019). Multivariate Logistic regression analysis was used to predict risk factors for sarcopenia. Results Of 156 patients in our series, incidence of malnutrition was 59.0% and incidence of sarcopenia was 29.5%, and they were 20.5% and 7.7% in 39 patients with Child-Pugh class A, 50.0% and 25.0% in 48 patients with class B and 87.0% and 44.9% in 69 patients with class C, significantly different among them (P<0.05); age, basic mass index (BMI), serum albumin level and SGA score in 46 patients with sarcopenia were (64.1±12.5)yr, (19.3±2.2)kg/m², (24.1±3.9)g/L and (21.3±3.4) points, significantly different as compared to [(54.7±11.2)yr, (23.9±3.0) kg/m², ((34.3±4.8)g/L and (28.7±4.0)point, all P<0.05] in 110 patients without sarcopenia; multivariate Logistic regression analysis showed that BMI(OR=0.683), serum albumin level (OR=0.631) and SGA score (OR=0.653) were all risk factors for occurrence of sarcopenia in patients with LC (P<0.05). Conclusion Malnutrition is common in patients with hepatitis B-induced LC, and the risk of sarcopenia is also relatively high. Clinicians should take these incidents into consideration and deal with as early as possible.

Key words: Liver cirrhosis, Malnutrition, Sarcopenia, Risk factors