Abstract: Objective This study was conducted to summarize clinical feature, risk factors and prognosis of patients with extra-liver abscesses(ELA) and decompensated liver cirrhosis(DLC). Methods 79 DLC patients with ELA and 49 cirrhotics with liver abscesses (LA) were encountered in our hospital between October 2016 and October 2021, and all patients in the two groups were managed by antibiotic administration and local drainage or surgical operation. Bacterial culture and characterization were carried out routinely. Results The causes of LC in both groups were predominantly hepatitis B viral infections, accounting for 60.8% and 50.1%, respectively (P>0.05), and a significant lower proportion (2.5%)of concurrent biliary stones in the ELA group was foundas compared to (59.2%) in the LA group (P<0.05); there was no significant disparity in the prevalence of coexisting diabetes mellitus between the two groups(3.9% vs.22.4%(P>0.05); predominant causative organisms in both groups were gram-negative bacteria,withEscherichia Coli(22.5% vs. 17.6%) and KlebsiellaPneumoniae(20.0% vs. 35.3%) being the most prevalent; the abscess inELA group included skin and soft tissue abscess (SSTA) in 42 cases and deepabscess (DA) in 37 cases; the recovery rate in patients with ELA was 67.1%, much lower than91.8%(P＜0.05) in those with LA; the predisposing factors in patients with DA included recurrent fever, repeated hospitalization because of infection, liver failure and invasive manipulation, and delayed hospitalization was more common (P＜0.05). Conclusion ELA is frequently occurred in patients withDLC with a bleak prognosis, especially in those with DA, and the prevalent pathogens are Klebsiella Pneumoniae and Escherichia Coli. Refraining from predisposing factors and early seeing doctors might improve the prognosis.

Key words: Extra-liver abscess, Liver abscess, Liver cirrhosis, Clinical feature, Risk factors, Prognosis