Abstract: Objective To investigate the hospitalization costs in patients with hepatitis B liver cirrhosis from 2013 to 2015. Methods The hospitalization costs of 406 patients with hepatitis B liver cirrhosis in our hospital between 2013 and 2015 was investigated and the factors influencing the hospitalization cost was analyzed. Results The total costs of medical care in 114 patients with hepatitis B cirrhosis was （14008.32±465.65） yuan in 2013,（13292.68±362.05） yuan in 132 patients in 2014,and（10915.32±256.49） yuan in 130 patients in 2015,respectively;the proportion of medicine expenses in hospitalization costs from 2013 to 2015 was the highest,accounting for 45.7%,46.3% and 47.0%,respectively,followed by the test fee, accounting for 26.4%,26.4% and 27.0%,respectively;there were significant differences as respect to the total costs of hospitalization between patients with different ages,Child classes,peroid of hospital stay,type of anti-viral therapy and whether or not for second hospital admission and surgery（P<0.05）;in addition,there were statistically significant differences in the total hospitalization expenses among patients with gastrointestinal bleeding,ascites,hepatic encephalopathy and cancer （P<0.05）;multiple linear regression analysis showed that hepatitis B liver cirrhosis patients with Child class C,longer hospital stay,second admission,surgical treatment,combination anti-viral therapy and complications（such as gastrointestinal bleeding, ascites,hepatic encephalopathy and cancer） increased the medical costs（P<0.05）. Conclusion Reasonably shortening the hospital stay,strengthening the prevention and treatment of complications and less hospital admission might be the key to reduce the economic burden of patients with hepatitis B liver cirrhosis.

Key words: Liver cirrhosis, Hepatitis B, Hospitalization costs, Linear regression analysis