Abstract: Objective To analyze the clinical features,outcomes,prognosis and related risk factors of cirrhotic patients complicated with diabetes. Methods Retrospective analysis was conducted in 133 cases of cirrhotic patients complicated with diabetes and 137 random cases of cirrhotic patients without diabetes from January 2011 to December 2011;the clinical characteristics,biochemical examination,complications,classification of liver function and disease outcome were recorded and compared. Results Average age of cirrhotic patients complicated with diabetes and non-diabetic cirrhotic patients were（55.9±11.0） years and（50.2 ±12.0） years respectively,average hospital stays were（15.6±11.3） days and （12.8±8.4） days,fasting blood glucose were （9.8±5.5） mmol/L and （5.1±2.1） mmol/L,aspartate aminotransferase （AST） were（83.2±98.6） u/L and（65.3±88.8） u/L,albumin （ALB） were （29.1±4.7） g/L and （30.5±5.5） g/L,triglycerides were （1.1±0.9） mmol/L and （0.7±0.4） mmol/L,and serum sodium were （134.3±5.1） mmol/L and（135.8 ± 5.7） mmol/L,respectively （P<0.05 for all）. In patients with diabetes,the numbers of alcoholic causes,Child-Pugh C grade,ascites,spontaneous bacterial peritonitis,hepatic encephalopathy and hypertension were significantly higher than those without diabetes（11.3 vs 3.7%,26.3 vs 11.3%,36.8 vs 29.9%,33.8 vs 22.6%,18.0 vs 9.0% and 21.1 vs 2.9%,respectively,P<0.05 for all）;Meanwhile,the mortality during hospitalization of patients with diabetes was significantly higher than that of patients without diabetes（18.8 vs 9.5%,P<0.05）. The Logistic analysis revealed that advanced age,duration of hospitalization,hypertension,hyperglycemia and triglyceride were the risk factor for diabetes in cirrhotic patients（odds ratio were 1.054, 1.052,16.182,1.503 and 1.503 respectively,P<0.01 for all）. Conclusion Compared with cirrhotic patients without diabetes,liver function and prognosis of cirrhotic patients with diabetes was poorer. Diabetes may contribute to the poor prognosis of patients with cirrhosis.

Key words: Cirrhosis, Diabetes, Logistic analysis, Risk factor, Prognosis