Abstract: Objective The aim of this study was to investigate the liver function test and hepatic blood flow parameter changes in children with benign liver diseases after living donor liver transplantation (LDLT). Methods 47 patients with benign liver diseases including congenital biliary atresia in 36 cases and glycogenosis in 11 cases, were encountered in our hospital between April 2019 and April 2022, and all underwent left-leaf LDLT. Serum total bilirubin (TBIL), albumin (ALB), international normalized ratio (INR) of prothrombin time and alanine transaminase (ALT) levels were detected routinely. The portal flow volume (PFV), portal flow index (PFI), hepatic flow volume (HFV) and hepatic flow volume index (HFI) were measured by ultrasonography. Results At presentation, serum TBIL, ALB, INR and ALT levels in our series were (226.3±35.8)μmol/L, (32.9±6.1)g/L, (1.2±0.2) and (79.8±25.1)U/L, one day after operation, they changed to (126.3±29.5)μmol/L, (30.1±5.3)g/L, (1.4±0.3) and (427.5±112.6)U/L, and they gradually returned to normal; at admission, the HFV, HFI, PFV and PFI in our series were (81.6±12.5)ml/min, (31.2±10.5) ml/min.100 g, (568.9±126.8)ml/min and (315.6±96.5)ml/min.100 g, one day after surgery, they changed to (134.7±52.8)ml/min, (58.8±24.2)ml/min.100 g, (1128.3±572.6)ml/min and (552.7±242.4)ml/min.100 g, and thereafter, they gradually returned to normal; 13 days and 15 days after operation, two children died of acute liver failure; one month after LDLT, 45 children recovered with normal liver function tests; during the follow-up period, no untoward complications of hepatic vessels was found in the survivals. Conclusion The liver function tests and hepatic vascular parameters could changes regularly, which might help judge the states of transplants, and should carefully surveyed.

Key words: Congenital biliary atresia, Glycogenosis, Living donor liver transplantation, Hepatic flow parameters, Children