Abstract: Objective The aim of this study was to explore the cardiac structural and functional changes in patients with hepatitis B cirrhosis after undergoing transjugular intrahepatic portosystemic shunt (TIPS). Methods 48 patients with hepatitis B-induced liver cirrhosis (LC) were encountered in our hospital between January 2018 and June 2021, and all underwent TIPS. The cardiac structural and functional parameters, including indexed right atrial volume (RAVI), indexed right ventricular end-diastolic volume (RVEDVI), indexed right ventricular end-systolic volume (RVESVI), indexed right ventricular stroke volume (RVSVI), right ventricular ejection fraction (RVEF), indexed left atrial volume (LAVI), indexed left ventricular end-diastolic volume (LVEDVI), indexed left ventricular end-systolic volume (LVESVI), indexed left ventricular stroke volume (LVSVI), left ventricular ejection fraction (LVEF) and indexed left ventricular myocardial mass (LVEDMI) were detected by cardiovascular magnetic resonance imaging (CMR). The RA area, tricuspid annular plane systolic excursion (TAPSE), LAVI, LVEF and ratio of E/e' were detected by echocardiography. Results At the end of six months after TIPS, the RAVI, RVEDVI, RVESVI, RVSVI, LAVI, LVEDVI, LVESVI, LVSVI and LVEDMI changed greatly as compared to before TIPS in the 48 patients with LC (P<0.05); the RA area, LAVI and ration E/e' echocardiography six months after TIPS were 18(15, 24)cm², 32(28, 45)ml/m² and 11(8,16), significantly different as compared to 16(12,19)cm², 23(20, 27)ml/m² and 8(5, 10)at presentation(P<0.05). Conclusion The heart volume increases and eccentric left ventricular hypertrophy occurs after TIPS in patients with LC, and their impact on cardiac functions needs further investigation.

Key words: Liver cirrhosis, Transjugular intrahepatic portosystemic shunt, Cardiovascular magnetic resonance imaging, Cardiac structure