肝侧叶肝切除术治疗肝胆管结石合并胆管狭窄患者近期疗效研究*

doi:10.3969/j.issn.1672-5069.2022.01.032

Abstract

Abstract: Objective The aim of this study was to investigate the short-term efficacy of lateral lobe hepatectomy in treatment of patients with hepatolithiasis and biliary stricture. Methods 72 patients with hepatolithiasis and biliary stricture were enrolled in our hospital between January 2015 and January 2020, and 38 patients in the observation group received lateral lobe hepatectomy, and 34 in the control group underwent conventional surgery. All patients were followed-up for 12 months. Results The operation time, intraoperative blood loss and post-operational hospitalization stay in the observation were (177.4±20.7)min, (220.6±22.5) ml and (7.1±1.5)d, not significantly different compared to [(185.6±25.3)min, (226.2±23.7) ml and (7.5±2.0)d, P>0.05] in the control group; at the end of seven days after operation, serum ALT, AST and ALP levels in the observation were (35.5±4.2)U/L, (52.4±6.9)U/L and (61.5±6.2)U/L, all significantly lower than [(50.6±5.3)U/L, (79.8±7.2)U/L and (87.6±7.3)U/L, respectively, P<0.05] in the control; the stone clearance rate in the observation group was 100.0%, not significantly different compared to 97.1%(P>0.05) in the control; post-operationally, the complications, such as infection of incisional wound, Acute obstructive suppurative cholangitis, subphrenic abscess and bile leakage in the observation was 7.9%, significantly lower than 26.5%(P<0.05) in control; during followed-up period, the incidence of stone residual rate, stone recurrence rate and the need for re-surgery in the observation group were 0.0%, 2.6% and 2.6%, all significantly lower than 14.7%, 20.6% and 20.6%, respectively, in the control group (P<0.05). Conclusion The short-term efficacy of lateral lobe hepatectomy in treatment of patients with hepatolithiasis and biliary stricture in good, with lower incidence of postoperative complications, lower stone residual and stone recurrence, which warrants further clinical verification.

Key words: Hepatolithiasis, Biliary stricture, Lateral lobe hepatectomy, Therapy, Short-term efficacy

Bai Lei, Wang Zhipeng, Tuer Hongjiang. Tuxun, et al. Short-term efficacy of lateral lobe hepatectomy in treatment of patients with hepatolithiasis and biliary stricture[J]. Journal of Practical Hepatology, 2022, 25(1): 128-131.

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Short-term efficacy of lateral lobe hepatectomy in treatment of patients with hepatolithiasis and biliary stricture

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