螺旋CT测定肝脏体积评估乙型肝炎肝硬化患者肝脏储备功能的应用

doi:10.3969/j.issn.1672-5069.2020.05.027

Abstract

Abstract: Objective The aim of this study was to evaluate hepatic functional reserve using practical liver volumes (PLV) measured by enhanced CT scan in patients with hepatitis B liver cirrhosis (LC). Methods A total of 60 patients with hepatitis B LC underwent spiral CT examination in our hospital between June 2016 and February 2020. The PLV was calculated by Myrian XP Liver software and compared to theoretical liver volumes (TLV). The LC was divided into four class based on CT imaging. Results The LC in our series was found to be class 1 in 12, class 2 in 25, class 3 in 13 and class 4 in 10; the PLV in patients with class 1 was (996.2±145.5)cm³, significantly smaller than TLV 【(1440.2±106.2)cm³, P<0.05】, the PLV in patients with class 2 was (918.2±116.4)cm³, significantly smaller than TLV【(1408.8±92.0)cm³, P<0.05】, the PLV in class 3 was (852.4±70.8)cm³, much smaller than TLV【(1380.2±104.8)cm³, P<0.05】 and the PLV in patients with class 4 was (724.9±92.3)cm³, significantly smaller than TLV【(1352.1±88.2)cm³, P<0.05】; the PLV in 15 patients with Child-Pugh class Awas (985.2±250.8)cm³, significantly smaller than TLV【(1420.6±125.0)cm³, P<0.05】, the PLV in 31 patients with class B was (820.6±105.4)cm³, significantly smaller than TLV 【(1381.8±110.8)cm³, P<0.05】 and the PLV in 14 patients with Child-Pugh class C was (704.6±70.5)cm³, significantly smaller than TLV 【(1340.5±120.9)cm³, P<0.05】; the PLV in 14 patients with MELD score less than 10 was (960.6±162.5)cm³, much smaller than TLV【(1408.2±92.8)cm³, P<0.05】, the PLV in 28 patients with MELD score of 10 to 20 was (842.6±90.6)cm³, significantly smaller than TLV【(1372.4±108.0)cm³, P<0.05】, and the PLV in 18 patients with MELD score greater than 20 was (782.1±40.8)cm³, significantly smaller than TLV 【(1325.0±130.8)cm³, P<0.05】. Conclusion The actual liver volume measured by spiral CT scan might effectively evaluate the functional reservoir in patients with hepatitis B liver cirrhosis, which warrants further clinical investigation.

Key words: Liver cirrhosis, Spiral CT scan, Practical liver volumes, Theoretical liver volumes, Liver reservoir

Zhu Xiaoqiang, Jiang Kai, Pan Jing.. Evaluation of hepatic functional reserve using practical liver volumes measured by enhanced CT scan in patients with hepatitis B liver cirrhosis[J]. Journal of Practical Hepatology, 2020, 23(5): 711-714.

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Evaluation of hepatic functional reserve using practical liver volumes measured by enhanced CT scan in patients with hepatitis B liver cirrhosis

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