妊娠期肝内胆汁淤积症诊断与管理

doi:10.3969/j.issn.1672-5069.2020.01.042

Abstract

Chen Huiting, Zhou Yongjian. Diagnosis and management of patients with intrahepatic cholestasis of pregnancy[J]. Journal of Practical Hepatology, 2020, 23(1): 153-155.

[1] 中华医学会妇产科学分会产科学组.妊娠期肝内胆汁淤积症诊疗指南( 2015).中华妇产科杂志,2015,50( 7):481-485.
[2] Hillman SC, Stokes-Lampard H, Kilby MD. Intrahepatic cholestasis of pregnancy.BMJ,2016,353:1-2.
[3] 中华医学会肝病学分会、消化病学分会、感染病学分会.胆汁淤积性肝病诊断和治疗共识(2015).实用肝脏病杂志,2016,19(6):I-XI.
[4] Royal College of Obstetricians and Gynaecologists.Obstetric cholestasis ( Green-top Guid-eline No.43 ) ,April 2011 [J/OL].RCOG[2011-05-11]https: / /www.rcog.org.uk/globalassets/d-ocuments/guidelines/gtg_43.pdf.
[5] Ozkan S,Ceylan Y,Ozkan OV,et al. Review of a challenging clinical issue: Intrahepatic cholestasis of pregnancy.World J Gastroenterol, 2015,21(23):7134-7141.
[6] Savander M,Ropponen A,Avela K,et al. Genetic evidence of heterogeneity in intrahepatic cholestasis of pregnancy.Gut,2003,52: 1025-1029.
[7] 葛星,徐叶青.妊娠期肝内胆汁淤积症对分娩结局影响的出生队列研究中华流行病学杂志, 2016,37(2):187-191.
[8] Hardikar W, Kansal S, Oude Elferink RP, et al. Intrahepatic cholestasis of pregnancy: when should you look further? World J Gastroenterol, 2009, 15(9): 1126-1129.
[9] Mazhar SB, Rahim F, Furukh T. Fetomaternal outcome in triplet pregnancy. J Coll Physicians Surg Pak, 2008, 18(4):217-221.
[10] Ovadia C, Seed PT, Sklavounos A, et al. Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses .Lancet, 2019 , 393(10174):899-909.
[11] Chappell LC. Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial. Lancet, 2019,[ahead of print].
[12] Smolarczyk R, Grymowicz M, Sienko J, et al. Successful perinatal outcome in an early onset intrahepatic cholestasis of pregnancy with extremely high serum hepatic function tests. Gynecol Endocrinol, 2009, 25(7): 475-476.
[13] Estiú MC,Frailuna MA,Otero C. Relationship between early onset severe intrahepatic cholestasis of pregnancy and higher risk of meconium-stained fluid. PLoS One,2017,12(4):1-15.
[14] Geenes V,Chappell LC,Seed PT. Association of severe intrahepatic cholestasis of pregna-ncy with adverse pregnancy outcomes: a prospective population-based case-control study.Hepatology,2014,59 (4):1482-1491.
[15] Gabzdyl EM,Schlaeger JM. Intrahepatic cholestasis of pregnancy: acritical clinical review. J Perinat Neonat Nurs,2015,1:41-50.
[16] Mozurkewich E, Chilimigras J, Koepke E, et al. Indications for induction of labour: a best-evidence review. BJOG,2009, 116(5): 626-636.

Diagnosis and management of patients with intrahepatic cholestasis of pregnancy

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	Xu Xiaoyuan. Highlights of newly released guideline for diagnosis and treatment of liver cirrhosis [J]. Journal of Practical Hepatology, 2020, 23(1): 4-6.
[2]	Yang Kezhi, Lu Wei, Huang Dan, et al. Diagnostic value of gamma-glutamyl transpeptidase to cholinesterase ratio in predicting hepatic fibrosis in patients with chronic hepatitis B [J]. Journal of Practical Hepatology, 2020, 23(1): 14-17.
[3]	Ye Xirong, Lyu Zhihong, Jiang Feng, et al. Clinical value of transient elastography and two-dimensional shear wave elastography in the diagnosis of liver fibrosis in patients with chronic hepatitis B [J]. Journal of Practical Hepatology, 2020, 23(1): 18-21.
[4]	Chen Lili, Fu Maoxiong, Meng Xubiao, et al. Clinical value of fasting C-peptide in assessing the progression of liver fibrosis in patients with NAFLD and T2DM [J]. Journal of Practical Hepatology, 2020, 23(1): 38-41.
[5]	Liu Jian, Zhu Fengfa, Tang Juan. Ultrasonographic and biochemical features of patients with non-alcoholic heterogeneous fatty liver [J]. Journal of Practical Hepatology, 2020, 23(1): 42-45.
[6]	Zhou Xiaoxu, Zhang Huajie. Evaluation of fetal cardiac functions by velocity vector imaging in pregnant women with intrahepatic cholestasis of pregnancy [J]. Journal of Practical Hepatology, 2020, 23(1): 62-65.
[7]	Wang Jingjing, Li Chuntao, Zhou Weizhen. Urineretinol binding protein levels in patients with hepatitis B-induced decompensated liver cirrhosis as the index for acute kidney injury [J]. Journal of Practical Hepatology, 2020, 23(1): 74-77.
[8]	Liu Xiao, He Nian’an, Ye Xianjun, et al. Application of contrast-enhanced ultrasound in differential diagnosis of hepatocellular carcinoma and liver metastases [J]. Journal of Practical Hepatology, 2020, 23(1): 94-97.
[9]	Shi Yingying, Wang Yuanxi. Application of liver imaging report and data management system in diagnosis of hepatocellular carcinoma in CT and MR examinations [J]. Journal of Practical Hepatology, 2020, 23(1): 98-101.
[10]	Gao Li, Gao Yi, Yin Qiuping. Clinical value of CT perfusion imaging combined with color Doppler sonography in the diagnosis of hepatic nodular lesions [J]. Journal of Practical Hepatology, 2020, 23(1): 106-109.
[11]	Wang Xiuqing, Ma Yanjun, Zhan Jinli. Imaging feature of patients with microvesicular polycystic liver [J]. Journal of Practical Hepatology, 2020, 23(1): 114-117.
[12]	Wang Chun, Chen Dongfeng. Fitz-Hugh-Curtis syndrome: What we know about? [J]. Journal of Practical Hepatology, 2020, 23(1): 149-152.
[13]	National Workshop on Fatty Liver, Alcoholic Liver Disease, Chinese Society of Hepatology; National Workshop on Liver, Metabolism, Chinese Society of Endocrinology, Chinese Medical Association. Committee of Hepatology, Chinese Research Hospital Association; Fatty Liver Expert Committee, Chinese Medical Doctor Association [J]. Journal of Practical Hepatology, 2019, 22(6): 787-792.
[14]	. Consensus on the diagnosis and therapy of hepatic fibrosis [J]. Journal of Practical Hepatology, 2019, 22(6): 793-803.
[15]	Tang Renyi, Hu Qunfeng, Peng Liqing.. Changes of serum lipids, liver function tests and estrogen levels in patients with intrahepatic cholestasis of pregnancy and its clinical significance [J]. Journal of Practical Hepatology, 2019, 22(6): 860-863.