Abstract: Objective To investigate the etiology of 202 patients with abnormal liver function tests. Methods 202 patients with abnormal liver function tests were admitted to our Department of Gastroenterology,Zhongshan Hospital between June 2011 and June 2008. The etiologic examination was routinely conducted. Results Out of the 202 patients with abnormal liver function tests,fatty liver disease was found in 62 cases （30.7%）,drug-induced liver injuries （DILI） in 56 cases （27.7%）,autoimmune liver disease （AILD） in 18 cases （8.9%）,hepatotropic virus infection in 18 cases （8.9%）,tumor in 9 cases（4.5%）,liver cirrhosis in 11（5.5%）,bile duct infection in 11（5.5%）,non-hepatotropic virus infection in 1（0.5%）,toxic injuries in 1（0.5%）,malnutrition in 2（1.0%） and liver injury with unknown cause in 13（6.4%）;the percentages of NAFLD,DILI and hepatotropic virus infection in youth accounted for 49.4%,16.9% and 10.8%,the percentages of DILI,NAFLD and AILD in middle aged group accounted for 34.3%,25.4% and 10.5%,and the percentages of DILI,AILD and tumor in elderly group accounted for 36.5%,15.4% and 13.5%;the percentages of NAFLD,DILI and hepatotropic viral infection in men accounted for 43.6%,20.0% nd 15.8%,and those of DILI,NAFLD and AILD in women accounted for 35.6%,17.8% and 14.9%. Conclusion The causes of abnormal liver function tests are complex and diverse,and the common causes of it in different ages and different genders differ,which might help the clinicians to deal with them.

Key words: Liver injuries, Etiology, Analysis