Abstract: Portal vein thrombosis （PVT） is a common complications in patients with liver cirrhosis,often as a predictor of poor prognosis. There is a controversial veiws about anticoagulation treatment in dealting with PVT as the high risk of hemorrhage in this settints. There is no at present guidelines related in this field. However,there are increasing evidence showing that anticoagulant therapy offers a high recanalization in patients with PVT,without an increase of gastrointestinal bleeding risks. The application of anticoagulation decreases the morbidity in patients with PVT and might improve the liver functions. Moreover,the earlier the anticoagulation started,the higher the rate of recanalization the patients could obtain. Thus,cirrhosis patients are recommended to start the anticoagulation after a definite diagnosis of PVT as soon as possible. If the anticoagulation therapy does not work,the transjugular intrahepatic portosystem shunt（TIPS） or thrombolysis are alternative strategy for patients with liver cirrhosis. The patients might acquire a high rate of vascular recanalization after TIPS,while this technique is very complicate. The thrombolysis should be taken carefully because of a high risk of bleeding.

Key words: Liver cirrhosis, Portal vein thrombosis, Thrombolysis, Transjugular intrahepatic portosystem shunt, Prophylaxis