Abstract: Objective To compare the technical and clinical efficacy of bare metal stent（BMS） and polytetrafluoroethylene（PTFE）-stentgraft of transjugular intrahepatic portosystemic shunt（TIPSS） in treatment of patients with portal hypertension（PH）.Methods 163 patients（56±12 ys，32.9 % females） with PH receiving TIPSS were recuited in this study，and 80 patients received BMS and 83 received PTFE-stentgraft.Results The technical success rate was 97.5% due to four unsuccessful interventions. The portosystemic gradient decreased from （16.1±4.8） mmHg to（5.1±2.1） mmHg in the successful series. There was no significant differences as respect to technical success rate and portosystemic gradient decrease between the two groups；Kaplan-Meier analysis yielded significant differences in primary patency after 14 days，6 months and 2 years thereafter in favour of the stentgraft；Both groups showed good clinical results without significant difference in 1-year survival and hepatic encephalopathy occurrence；Costs to establish TIPSS and maintain 2-year follow-up for constant patency were 66570 yuan in BMS group and 70455 yuan in PTFE-stentgraft.Conclusion TIPSS is a safe and effective procedure to manage portal hypertension. Both BMS stent and PTFE-stentgraft enable good technical and clinical outcomes with low complication rate，while the primary patency rate is clearly in favour of the stentgraft with a relative high costs.

Key words: Portal hypertension, Transjugular intrahepatic portosystemic shunt, Bare metal stent, polytetrafluoroethylene-stentgraft