JOURNAL OF PRACTICAL HEPATOLOGY ›› 2014, Vol. 17 ›› Issue (2): 210-213.doi: 10.3969/j.issn.1672-5069.2014.02.028

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Hepatitis B viral gene mutation and disease progression in patients with hepatitis B virus infection

Li Fan, Chen Guofeng,Xu Dongping.   

  1. Center for Diagnosis and Treatment of Liver Disease,302nd Hospital,Beijing 10085,China
  • Received:2013-05-20 Online:2014-08-20 Published:2016-04-15

Abstract: Hepatitis B virus infection may result in acute or chronic hepatitis B. The outcomes of chronic hepatitis B virus infection include chronic hepatitis,cirrhosis,hepatocellular carcinoma and liver failure. Host,virus factors and their interactions affect disease progression. The change in biological characteristics caused by HBV gene mutations is one of the pivotal factors determining the outcomes of HBV infection.

Key words: Hepatitis B, Gene mutation, Disease prognosis