JOURNAL OF PRACTICAL HEPATOLOGY ›› 2014, Vol. 17 ›› Issue (2): 198-201.doi: 10.3969/j.issn.1672-5069.2014.02.025

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Progress in clinical diagnosis and treatment of patients with liver failure and hepatorenal syndrome

Li Jinge, Nie Qinghe.   

  1. Centre of Diagnosis and Treatment for Infections Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038,China
  • Received:2013-12-05 Online:2014-08-20 Published:2016-04-15

Abstract: Hepatorenal syndrome(HRS) is one of serious complications of severe liver diseases including liver failure, decompensated cirrhosis and liver cancer. Although the diagnostic criteria for HRS has been defined clearly, the specific diagnostic indicators are lack in clinical practice. HRS is just a clinical exclusion diagnosis. Once the symptom of significant reduction in the amount of urine with increased serum creatinine levels suddenly appears,it might be the early signs of HRS. As respect to the treatment of HRS,combination of vasoconstrictors and albumin,TIPS,CRRT and MARS could improve renal function, mainly serving as a bridge for liver transplantation. So far,liver transplantation is the most effective treatment for HRS.

Key words: Hepatorenal syndrome, Pre-renal azotemia, Acute tubular necrosis, Diagnosis