JOURNAL OF PRACTICAL HEPATOLOGY ›› 2011, Vol. 14 ›› Issue (2): 138-141.doi: 10.3969/j.issn.1672-5069.2011.02.020

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The correlation between CT enhancement patterns and tumor angiogenesis in the edge of hepatocellular carcinoma

SHI Huiping,LIU Xiaoyu,LI Dongmei,et al.   

  1. CT Room,Department of Pathology,the First Affiliated Hospital,Qiqihaer Medical College,Qiqihaer 161042
  • Received:2010-11-22 Revised:2016-04-15 Online:2011-04-10 Published:2016-04-15

Abstract: Objective To investigate the correlation between the enhancement characteristics and tumor angiogenesis in the edge of hepatocellular carcinoma. Methods The characteristics of CT enhancement confirmed by preoperative CT scan and contrast CT of hepatic arterial and portal phase were studied in 38 patients with hepatocellular carcinoma. CD34 was detected by immunohistochemistry in the tumor tissues. Results The tumors with clear edge shown on plain CT with thin or thick envelope were in the manner of expansive growth,while the tumors with unclear edge were in invasive growth;there was a higher probability of invasion for tumors with unclear and high-density,and a probable transfer for tumors with rich edge angiogenesis;relatively,there was lower transfer for tumors with low-density and fewer new blood vessels. Conclusion Dynamic enhanced CT scan can show the CT enhancement characteristics of the tumor,which might reflect the pathological changes and have great significance for clinical guidance.

Key words: Hepatocellular carcinoma, CD-34, Pathology, X-ray computed tomography