实用肝脏病杂志 ›› 2011, Vol. 14 ›› Issue (5): 349-350.doi: 10.3969/j.issn.1672-5069.2011.05.012

• 论著 • 上一篇    下一篇

肝硬化发生自发性细菌性腹膜炎的危险因素分析

占国清,谭华炳,李芳,李儒贵,李金科   

  1. 442000 湖北省十堰市 湖北医药学院附属人民医院肝病研究所
  • 收稿日期:2011-05-16 出版日期:2011-10-15 发布日期:2016-04-14
  • 作者简介:占国清 男,45岁,医学硕士,主任医师。主要从事肝病的临床和分子生物学研究。E-mail:syrmhospital@yahoo.com.cn

Risk factors of spontaneous bacterial peritonitis in patients with liver cirrhosis

ZHAN Guoqing,TAN Huabing,LI Fang,et al.   

  1. Institute of Hepatology,People’s Hospitol,Hubei Medicine College,Shiyan 442000,China
  • Received:2011-05-16 Online:2011-10-15 Published:2016-04-14

摘要: 目的 探讨肝硬化自发性细菌性腹膜炎(SBP)发生的危险因素。方法 398例肝硬化患者被分为SBP组(135例)和无SBP组(263例),比较两组年龄、性别、病程、既往SBP史、腹水时间、糖尿病史、腹水总蛋白、消化道出血、肝功能Child-Pugh分级、抗生素预防、重要生化及凝血指标等因素。结果 两组患者在既往SBP史、腹水时间、糖尿病史、腹水总蛋白、消化道出血、Child-Pugh分级、抗生素预防、血Na+、TBil、ALB、PT等方面差异有非常显著性意义(P<0.01)。结论 肝硬化SBP发生与一些因素高度相关,应予以及时有效的防治,以减少SBP的发生。

关键词: 肝硬化, 自发性细菌性腹膜炎, 危险因素

Abstract: Objective To explore the risk factors of spontaneous bacterial peritonitis in patients with liver cirrhosis. Methods 398 patients with liver cirrhosis were divided into spontaneous bacterial peritonitis group(n=135)and non-spontaneous bacterial peritonitis group(n=263). The predisposing factors in the two groups were compared. Results There were significant differences in history of SBP,ascites period,diabetes mellitus,total protein in ascitic fluid,digestive tract hemorrhage,Child-Pugh grades,antibiotic prophylaxis,blood Na+,serum TBil,ALB and PT between the two groups(P<0.01). Conclusions The incidences of SBP is related to some factors,which might be properly managed in order to reduce the occurrence of spontaneous bacterial peritonitis in patients with liver cirrhosis.

Key words: Liver cirrhosis, Spontaneous bacterial peritonitis, Risk factors