[1] 中华医学会肝病学分会和感染病学分会.慢性乙型肝炎防治指南(2022年版).实用肝脏病杂志,2023,26(3)S18-39. [2] Yuan J, Lu ZK, Xiong X,et al. Impact of national volume-based procurement on the procurement volumes and spending for antiviral medications of hepatitis B virus. Front Pharmacol, 2022, 13:842944. [3] 中华医学会肝病学分会. 扩大慢性乙型肝炎抗病毒治疗的专家意见. 中华肝脏病杂志, 2022, 30(2): 131-136. [4] European Association for the Study of the Liver. EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection. J Hepatol,2017,67(2):370-398. [5] Gordon SC, Krastev Z, Horban A, et al. Efficacy of tenofovir disoproxil fumarate at 240 weeks in patients with chronic hepatitis B with high baseline viral load. Hepatology, 2013, 58(2):505-513. [6] Chan HLY, Fung S, Seto WK, et al. Tenofovir alafenamide versus tenofovir disoproxil fumarate for the treatment of HBeAg positive chronic hepatitis B virus infection: a randomized, double-blind, phase 3, non-inferiority trial. Lancet Gastroenterol Hepatol, 2016, 1(3):185-195. [7] Lin MH, Li HQ, Zhu L, et al. Liver fibrosis in the natural course of chronic hepatitis B viral infection: a systematic review with meta-analysis. Dig Dis Sci, 2022, 67(6):2608-2626. [8] Kim GA, Lim YS, Han S, et al. High risk of hepatocellular carcinoma and death in patients with immune-tolerant-phase chronic hepatitis B. Gut, 2018, 67(5):945-952. [9] 赵素贤, 常楚笛, 南月敏. 精准免疫分期指导慢性HBV感染者尽早启动抗病毒治疗. 中华肝脏病杂志, 2023, 31(3):228-232. [10] Lee H, Jang S, Ahn SH, et al. Cost-effectiveness of antiviral therapy in untreated compensated cirrhosis patient with serum HBV-DNA level<2000 IU/mL. Hepatol Int, 2022,16(2):294-305. [11] Huang DQ, Tamaki N, Lee HW, et al. Outcome of untreated low-level viremia versus antiviral therapy-induced or spontaneous undetectable HBV-DNA in compensated cirrhosis. Hepatology, 2023, 77(5):1746-1756. [12] Wong RJ, Kaufman HW, Niles JK, et al. Simplifying treatment criteria in chronic hepatitis B: reducing barriers to elimination. Clin Infect Dis, 2023, 76(3):e791-e800. [13] Chang TT, Gish RG, de Man R, et al. A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N Engl J Med, 2006, 354(10):1001-1010. [14] Agarwal K, Brunetto M, Seto WK, et al. 96 weeks treatment of tenofovir alafenamide vs. tenofovir disoproxil fumarate for hepatitis B virus infection. J Hepatol, 2018, 68(4):672-681. [15] Buti M, Gane E, Seto WK, et al. TAF vs. tenofovir disoproxil fumarate for the treatment of patients with HBeAg-negative chronic hepatitis B virus infection: a randomised, double-blind, phase 3, non-inferiority trial. Lancet Gastroenterol Hepatol, 2016,1(3):196-206. [16] Chan HL, Fung S, Seto WK, et al. TAF vs. tenofovir disoproxil fumarate for the treatment of HBeAg-positive chronic hepatitis B virus infection: a randomised, double-blind, phase 3, non-inferiority trial. Lancet Gastroenterol Hepatol,2016, 1(3):185-195. [17] Liu Z, Jin Q, Zhang Y,et al. 96-week treatment of tenofovir amibufenamide and tenofovir disoproxil fumarate in chronic hepatitis B patients. J Clin Transl Hepatol, 2023, 11(3):649-660. [18] Ning Q, Han M, Sun Y, et al. Switching from entecavir to pegIFN alfa-2a in patients with HBeAg-positive chronic hepatitis B: a randomised open-label trial (OSST trial). J Hepatol, 2014, 61(4):777-784. [19] Hu P, Shang J, Zhang W, et al. HBsAg loss with peg-interferon alfa-2a in hepatitis B patients with partial response to nucleos(t)ide analog: new switch study. J Clin Transl Hepatol, 2018, 6(1): 25-34. [20] 程齐齐, 杨丽霞, 蔡天盼,等. 核苷(酸)类似物初治的慢性乙型肝炎患者发生低病毒血症的影响因素及其动态变化分析. 临床肝胆病杂志, 2022, 38(12): 2716-2722. [21] Zhang Q, Peng H, Liu X, et al. Chronic hepatitis B infection withlow level viremia correlates with the progression of the liver disease. J Clin Transl Hepatol, 2021, 9(6):850-859. [22] Sun Y, Wu X, Zhou J,et al. Persistent low level of hepatitis B virus promotes fibrosis progression during therapy. Clin Gastroenterol Hepatol, 2020, 18(11):2582-2591,e6. [23] Kim JH, Sinn DH, Kang W,et al. Low-level viremia and the increased risk of hepatocellular carcinoma in patients receiving entecavir treatment. Hepatology, 2017, 66(2):335-343. [24] Lee SB, Jeong J, Park JH, et al. Low-level viremia and cirrhotic complications in patients with chronic hepatitis B according to adherence to entecavir. Clin Mol Hepatol. 2020,26(3):364-375. [25] Zhang Q, Cai DC, Hu P,et al. Low-level viremia in nucleoside analog-treated chronic hepatitis B patients. Chin Med J (Engl), 2021, 134(23):2810-2817. [26] Li ZB, Li L, Niu XX,et al. Switching from entecavir to tenofovir alafenamide for chronic hepatitis B patients with low-level viraemia. Liver Int, 2021, 41(6):1254-1264. |